Peristasis is introduced as a continuation of the dimension defined by the concepts of homeostasis and allostasis. Homeostasis is the simplest form of adaptation and can be implemented by a single-level control mechanism, referred to also as a T1-system. Allostasis is more elaborate and requires a minimum of two levels of control i.e., a T2-system. Peristasis is an even more adaptive function of biological systems than allostasis and involves hierarchical organization of three levels of control, or a T3-system. The term peristasis is derived from Ancient Greek “peri” meaning around. Peristasis refers to the capability of an adaptive system to adjust by detecting the properties of the current situation in the surrounding world using previous experiences with similar situations. A peristatic system activates a set of homeostatic mechanisms that are, according to the past experience, most appropriate for that particular situation.

A successful peristasis reduces allostatic load.

The concept of peristasis is a part of the theory of practopoiesis.

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